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產(chǎn)品名稱: CCR5 antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
CCR5 antibody迅速增長(zhǎng)的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。CCR5 antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
CCR5 antibody
的詳細(xì)介紹
CCR5 antibodyProduct Profile
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Product Name
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Rabbit anti-CCR5 polyclonal antibody - middle region
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Antibody Type
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Primary Antibodies
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Immunogen
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The immunogen for anti-CCR5 antibody: synthetic peptide directed towards the middle region of human CCR5
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CCR5 antibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Species Reactivity
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BovineHumanMousePigRabbitSheep
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Concentration
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1mg/ml
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Purification
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Affinity purified
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CCR5 antibodyTarget Information
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Gene Symbol
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CCR5
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Gene Synonyms
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CC-CKR-5
CCCKR5
CD195
CKR-5
CKR5
CMKBR5
IDDM22
More
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Gene Full Name
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Chemokine (C-C motif) receptor 5 (gene/pseudogene)
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Gene Summary
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CCR5 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this protein was also detected in a promyeloblastic cell line, suggesting that CCR5 may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.
More
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Alternative Names
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CC-CKR-5
CCCKR5
CD195
CKR-5
CKR5
CMKBR5
IDDM22
More
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Molecular Weight(MW)
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41kDa
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Sequence
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352 amino acids
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CCR5 antibodyDatabase Links
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Entrez Gene
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1234
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SwissProt ID
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P51681
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Protein Accession
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NP_000570
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CCR5 antibodyApplication
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Western blot
0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human heart
Additional Information
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Form
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Liquid
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Storage Instructions
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Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
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Storage Buffer
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phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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