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產(chǎn)品名稱(chēng): ZNF496 antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
抗ZNF496 antibody的**原：針對(duì)人ZNF496的中間區(qū)域的合成肽，ZNF496 antibody包含SCAN盒，KRAB-A結(jié)構(gòu)域和四個(gè)共有C2H2型鋅指，其前面是獨(dú)特的手指衍生物，本文稱(chēng)為C2HR基序。 C2HR基序用于介導(dǎo)與Zn（II）依賴(lài)的NSD1的富含半胱氨酸（C5HCH）結(jié)構(gòu)域的蛋白質(zhì) - 蛋白質(zhì)相互作用。
ZNF496 antibody
的詳細(xì)介紹
ZNF496 antibody Product Profile
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Product Name
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Rabbit anti-ZNF496 polyclonal antibody - middle region
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Antibody Type
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Primary Antibodies
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Immunogen
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The immunogen for anti-ZNF496 antibody: synthetic peptide directed towards the middle region of human ZNF496
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ZNF496 antibody Key Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Species Reactivity
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BovineDogHorsePigSheep
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Concentration
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1mg/ml
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Purification
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Affinity purified
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ZNF496 antibody Target Information
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Gene Symbol
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ZNF496
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Gene Synonyms
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ZNF496
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Gene Full Name
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Zinc finger protein 496
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Gene Summary
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ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.
More
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Alternative Names
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MGC15548
NIZP1
ZKSCAN17
ZFP496
More
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Molecular Weight(MW)
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67kDa
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Sequence
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587 amino acids
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ZNF496 antibody Database Links
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Entrez Gene
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84838
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SwissProt ID
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Q96IT1
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Protein Accession
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NP_116141
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ZNF496 antibody Application
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Application
WB Suggested Anti-ZNF496 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: PANC1 cell lysate
Additional Information
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Form
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Liquid
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Storage Instructions
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Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
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Storage Buffer
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phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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