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產(chǎn)品名稱: CXCR4 antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
CXCR4 antibody迅速增長(zhǎng)的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。CXCR4 antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
CXCR4 antibody
的詳細(xì)介紹
CXCR4 antibodyProduct Profile
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Product Name
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Rabbit anti-CXCR4 polyclonal antibody - N-terminal region
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Antibody Type
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Primary Antibodies
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Immunogen
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The immunogen for anti-CXCR4 antibody: synthetic peptide directed towards the N terminal of human CXCR4
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CXCR4 antibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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FCIHCWB
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Species Reactivity
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HumanRabbit
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Concentration
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1mg/ml
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Purification
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Affinity purified
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CXCR4 antibodyTarget Information
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Gene Symbol
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CXCR4
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Gene Synonyms
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CD184
D2S201E
FB22
HM89
HSY3RR
LAP3
LCR1
LESTR
NPY3R
NPYR
NPYRL
NPYY3R
WHIM
More
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Gene Full Name
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Chemokine (C-X-C motif) receptor 4
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Gene Summary
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CXCR4 is a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
More
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Alternative Names
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CD184
D2S201E
FB22
HM89
HSY3RR
LAP3
LCR1
LESTR
NPY3R
NPYR
NPYRL
NPYY3R
WHIM
More
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Molecular Weight(MW)
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40kDa
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Sequence
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352 amino acids
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CXCR4 antibodyDatabase Links
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Entrez Gene
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7852
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SwissProt ID
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P61073
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Protein Accession
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NP_003458
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CXCR4 antibodyApplication
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Immunohistochemical
Sample Type: human colon tissues infected ex-vivo with HIV-1
Green: Primary
Blue: DAPI
Primary Dilution: 1:100
Secondary Antibody: Donkey anti-Rabbit AF 488
Secondary Dilution: 1:500
Image Submitted By: Chiara Foglieni
San Raffaele Scientific Institute, Milan, Italy
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Immunohistochemistry
Immunohistochemistry with HMEC-1 and A549 cells tissue
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Western blot
Positive Control: Lane 1: 20ug mouse brain extract Lane 2: 20ug mouse brain extract
Primary Antibody Dilution : 1:500
Secondary Antibody : Anti rabbit-HRP
Secondry Antibody Dilution : 1:5,000
Submitted by: Scott Wilson, University of Alabama at Birmingham
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Western blot
CXCR4 antibody - N-terminal region validated by WB using 721_B cell Lysate at 0.2-1 ug/ml.
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Western blot
CXCR4 antibody - N-terminal region validated by WB using human microvascular endothelial cells (25ug) at 1:1000.
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Western blot
0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 721_B cell lysate
Additional Information
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Form
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Liquid
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Storage Instructions
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Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
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Storage Buffer
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phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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