| Product Name | Rabbit anti-BAK1 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | BAK1 |
|---|---|
| Gene Synonyms |
BAK
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BAK-LIKE BCL2L7 CDN1 MGC117255 MGC3887 |
| Gene Full Name | BCL2-antagonist/killer 1 |
| Gene Summary |
BAK1 belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
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| Alternative Names |
BAK
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BAK-LIKE BCL2L7 CDN1 MGC117255 MGC3887 |
| Molecular Weight(MW) | 23kDa |
| Sequence | 211 amino acids |
| Entrez Gene | 578 |
|---|---|
| SwissProt ID | Q16611 |
| Protein Accession | NP_001179 |
Titration: 1.0 ug/ml
Positive Control: Fetal Heart
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |