CD3 Peptides
Product Name: CD3 Peptides
Cat. Number: hz-0765P
Quantity size: 500ug
Source: Synthetic Peptide
Form: lyophilized powde
Purity: ≥95% (Purified by HPLC)
Storage: Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application: Immunology research
Blocking Peptide of The hz-0765R Antibody
Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].
Also known as: CD3 epsilon; CD3e; CD3e antigen epsilon polypeptide (TiT3 complex); CD3E antigen epsilon polypeptide; CD3E antigen, epsilon subunit; CD3e molecule epsilon; CD3e molecule, epsilon (CD3 TCR complex); CD3e molecule, epsilon (CD3-TCR complex); CD3E_HUMAN; IMD18; T cell antigen receptor complex epsilon subunit of T3; T cell surface antigen T3/Leu 4 epsilon chain; T cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景：該基因編碼的蛋白質(zhì)的CD3ε多肽，連同CD3γ-δ和Zeta和T細胞受體α/β和γδT細胞受體CD3復(fù)合物形成的異源二聚體。這種復(fù)合物在抗原識別與細胞內(nèi)信號轉(zhuǎn)導(dǎo)通路的偶聯(lián)中起著重要作用。編碼ε、γ和δ多肽的基因位于11號染色體上的同一簇中。ε-多肽在T細胞發(fā)育中起著重要作用。這個基因的缺陷導(dǎo)致**缺陷。該基因也與女性I型糖尿病易感性有關(guān)。[由RefSeq提供，月2008日]。
又名：CD3εεεε多肽抗原；；（tit3復(fù)雜）；εε多肽抗原；抗原CD3ε，ε亞基；CD3εεεε分子；分子（CD3 TCR復(fù)合物分子）；ε，ε（CD3-TCR復(fù)合物）；cd3e_human；imd18；T細胞抗原受體復(fù)合物ε亞基T3；T細胞表面抗原T3 /亮氨酸4ε鏈；T細胞表面的糖蛋白CD3ε鏈；T細胞表面抗原T3 /亮氨酸-4鏈；T細胞表面糖蛋白CD3ε鏈；T3E；TCRE。
